WVOX reaches many more listeners, worldwide, by streaming live, online. As of July 12, 2010, WVOX can also be heard on the HD4 subchannel of its FM sister station, WVIP.

Programming is primarily locally produced information and talk, including programs presented by local citizens and interest groups. O'Shaughnessy hosted a daily talk show on the station for more than 50 years, featuring interviews with many major U.S. politicians, authors, and entertainers. O'Shaughnessy, who has been called "the voice of Westchester", is fond of calling WVOX the "quintessential community radio station in America", a label first applied to the station by the Wall Street Journal. Referring to the station's citizen-produced content, a New York Daily News critic described WVOX as a "glorious hodgepodge, much of which even O'Shaughnessy can't get excited about."

In 2005, O'Shaughnessy was one of the first 25 people to be inducted into the new New York State Broadcasters Hall of Fame by the New York State Broadcasters Association. He was honored for his long record as a champion of free speech under the First Amendment. A history of the broadcasters' association published in 2005 described O'Shaughnessy as "happily turn[ing] over the airwaves to their rightful owners, the residents of the influential community he serves."

WVOX airs a diverse lineup of talk, music, sports, and religious programming. Among its various offerings are:

(Semi-) Daily Shows

Good Morning, Westchester! - Hosted by TJ McCormick, the series airs weekdays from 6-9 AM and offers news, interviews, listener call-ins, and entertainment reports.

Music From the Forum - Nick Sarames plays MOR music, primarily from the 60s and 70s (although other decades are featured) every afternoon at varying times between 3-6 PM.

The Fred Dicker Show - Airing weekday afternoons from 4-5 PM, this political talk show hosted by the longtime New York Post columnist had been a ratings draw for several years on originating station WGDJ in Albany, and was added to the WVOX lineup in December 2011. The series regularly features well-known state politicians as guests, including Governor Andrew Cuomo.

Weekly Shows

Weekdays

Mondays:

The Z Travel and Leisure Show - Airing alternate Monday nights at 8 PM, the husband-and-wife team of Art and Susan Zuckerman discuss noteworthy places in the New York metropolitan area, as well as interviewing noteworthy people, both locally and elsewhere.

Tuesdays:

The State of the City - Airing Tuesdays at 9 AM, New Rochelle Mayor Noam Branson and City Manager Chuck Strome discuss various issues concerning the city.

Wednesdays:

The Advocates - Airing Wednesdays at noon, Richard J. Garfunkel presides over this issues-oriented discussion show.

Thursdays:

The Smoothie Lounge - Airing Thursdays at 8 PM, Chuck Donegan hosts an hour of past and present smooth jazz music, meant for those who have been having a "rough day" or need to unwind, according to Donegan.

Fridays:

Conversations with Ernie Davis - Airing Fridays at 9 AM, the Former Mayor of nearby Mount Vernon hosts this discussion show.

Say Hey! with Mark Lungariello - Airing Fridays at 11 AM, hosted by WAG magazine columnist and Westchester County Business Journal contributing editor Mark Lungariello.

Weekends

Saturdays:

The Metro Golf Show - Airing Saturday mornings at 8:30 AM, co-hosts Bill Meth and Tom Mariam preside over this half-hour program, called the "Best Local Radio Show Covering Golf" by the NY Daily News; among its noteworthy guests have been Arnold Palmer, Annika Sorenstam, Jack Nicklaus, and celebrities such as Derek Jeter and Donald Trump.

Radio Chuck - Airing Saturday nights at 10 PM, Chuck Donegan spins the tunes on this 3-hour music program, which features a variety of songs whose titles and/or artists all tie into a different theme each week (the 10 PM show is a "best of" rerun from the year before, the 11 PM show is a new one, and 12 AM brings the commercial-free Midnight Hour, devoted to "smooth music perfect for the weekend").

Sundays:

Remember Then? - Airing Sundays at 11 AM, the team of Dennis Nardone and Tonny Guido preside over this 3-hour music show devoted to oldies, "the greatest music ever recorded" (Nardone and Guido also host Harrison Live, a Thursday afternoon talk/call-in show, and Nardone also co-hosted a revived version of What's Goin' On? with actor Vincent Pastore, which aired briefly on WVOX in early 2012). The Nick Golden Show - Airing Sunday nights at 9 PM, this sports talk/call-in show features observations on current events in the world of sports by Golden and his callers.

Additional weekend programming

In addition, WVOX airs religious services from local churches on weekends, with the syndicated Music of Your Life service rounding out the overnight and weekend schedule. The station also airs hourly news updates from Fox News Radio, with additional 1-minute updates also running at the half-hour and/or :45 marks for many shows.

Annual St. Patrick's Day Live Broadcast

Every St. Patrick's Day since 1960, WVOX has pre-empted its regular programming in favor of an all-day live remote from the holiday celebration at Dudley's Parkview, a bar/restaurant in New Rochelle. This yearly event features appearances by many of the station's on-air personalities, interviews with local residents, and an assortment of traditional Irish music.

50th Anniversary Celebration